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The beta-HIVS-induced lower of dUTPase inside the phosphoprotein fraction of DMS114 cells was confirmed utilizing immunoblotting. Therapy of the cells with beta-HIVS-induced fast reduction of dUTPase exercise. An antioxidant N-acetyl-cysteine inhibited both of those the reduction of phosphorylated dUTPase plus the induction of apoptosis by beta-HIV